Jun 15, 2026Caloric Restriction

Intermittent Fasting Works for Fat Loss, Not Proven Autophagy

Intermittent fasting can help reduce body fat, but human trials show no reliable calorie-independent edge—and claims of whole-body autophagy still outrun proof.

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Apr 29, 2026Nutrition

Time-Restricted Eating After Sleeve Weight Regain: Does It Help?

Can time-restricted eating improve weight regain after sleeve surgery? A close look at the lone direct trial, modest broader evidence, and trade-offs.

time-restricted eatingintermittent fastingcalorie restrictionweight regain

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Mar 28, 2026Epigenetics

Can Lifestyle Changes Turn Back the Epigenetic Clock?

An 8-week lifestyle trial reported a 3.23-year epigenetic-age difference. Larger studies support modest, clock-specific effects instead.

horvath clockdna methylationbiological agingintermittent fasting

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Mar 28, 2026Nutrition

16:8 Fasting for Resistant Hypertension: An Early Gut Signal

Can 16:8 fasting lower resistant hypertension through the gut microbiome? A two-week study raises the question, but leaves major clinical gaps.

intermittent fastingresistant hypertensiongut microbiomeakkermansia muciniphila

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Mar 28, 2026Nutrition

Can a 5-Day Fast Add to DASH for Blood Pressure?

A small randomized trial found supervised 5-day fasting before DASH improved systolic blood pressure at 3 months, but safety and replication matter.

intermittent fastingblood pressuredash dietgut microbiome

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Mar 26, 2026Nutrition

Meal Timing Works—Mostly Because It Helps You Eat Less

Time-restricted eating can improve weight and metabolic markers, but long-term trials suggest calorie reduction, not the clock, drives most benefits.

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Mar 21, 2026Nutrition

First Pediatric Time-Restricted Eating Trial Falls Short

First pediatric time-restricted eating trial finds families will try it—but at 12 weeks, it cannot show whether meal timing helps children with obesity or harms at home.

time-restricted eatingintermittent fastingpediatric obesityweight management

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Mar 19, 2026Nutrition

Intermittent Fasting, BDNF, and Depression: What Holds Up

Does intermittent fasting raise BDNF and ease depression? Human studies show fewer cravings for some people, but an uneven BDNF signal and no MDD trials.

intermittent fastingbdnffood addictiondopamine

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Mar 19, 2026Nutrition

Intermittent Fasting and Brain Fog: What Trials Actually Show

Intermittent fasting may improve weight and metabolic markers, but mental-clarity claims outrun human trials, while cognitive side effects remain unmeasured.

intermittent fastingmental claritybrain fogcalorie restriction

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Mar 18, 2026Nutrition

Can Any Diet Reverse Prediabetes? What the Best Review Found

Which diets and supplements actually reverse prediabetes? An umbrella review finds weak evidence, a modest vitamin D signal, and major research gaps.

prediabetesblood glucosevitamin ddiabetes prevention

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Mar 18, 2026Nutrition

Time-Restricted Eating and Sleep: What the Evidence Shows

Can earlier time-restricted eating improve sleep? Reviews of randomized trials find mixed results, while timing and chronotype may matter most.

time-restricted eatingintermittent fastingsleep qualitycircadian rhythm

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Mar 17, 2026Nutrition

TRE, Low-Carb Diets, and Thyroid Markers: What a Trial Found

A 12-week trial linked time-restricted eating and low-carb diets to cardiac enzyme and thyroid changes, but weight loss may explain them.

time-restricted eatingintermittent fastingmetabolic syndromelow-carb diet

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