Jun 26, 2026Cognitive Aging

Brain Energy and Aging: What Ketone Trials Actually Show

Can brain energy change with age? Metabolic syndrome tracks with higher brain energy costs, while ketone trials in MCI offer early, limited clues.

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Jun 16, 2026Metabolic Aging

Does Sitting Less Improve Liver Insulin Sensitivity?

A six-month trial found that sitting less did not clearly improve liver insulin sensitivity or liver fat—while weight-loss studies reveal why.

insulin sensitivityliver fatmetabolic syndromesedentary behavior

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Mar 29, 2026Nutrition

Spirulina for Metabolic Syndrome: What Evidence Shows

Can spirulina improve blood sugar, cholesterol, weight, or blood pressure? Review the human evidence, dose gaps, and limits for metabolic syndrome.

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Mar 28, 2026Nutrition

Can a 5-Day Fast Add to DASH for Blood Pressure?

A small randomized trial found supervised 5-day fasting before DASH improved systolic blood pressure at 3 months, but safety and replication matter.

intermittent fastingblood pressuredash dietgut microbiome

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Mar 27, 2026Nutrition

Why NAD+ Supplements May Miss the Problem in Diabetic Hearts

New diabetic-heart research links ACMSD to impaired NAD+ synthesis, while the only heart-failure NAD+ trial leaves HFpEF treatment unanswered in humans.

nad+heart failurehfpefglp-1 agonists

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Mar 22, 2026Metabolic Health

Artificial Light at Night and Metabolic Risk: What We Know

Bedroom and outdoor artificial light at night are linked to obesity, metabolic risk, and depression. Here is what the studies show—and cannot prove.

light exposuremetabolic syndromecircadian rhythmsleep disruption

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Mar 18, 2026Nutrition

Isomaltulose vs. Sucrose: A Modest Glucose Advantage

Isomaltulose may lower the 60-minute glucose peak by about 8 mg/dL versus sucrose. Here is what meta-analyses show—and what they cannot prove.

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Mar 17, 2026Nutrition

TRE, Low-Carb Diets, and Thyroid Markers: What a Trial Found

A 12-week trial linked time-restricted eating and low-carb diets to cardiac enzyme and thyroid changes, but weight loss may explain them.

time-restricted eatingintermittent fastingmetabolic syndromelow-carb diet

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Mar 17, 2026Nutrition

Does Preconception Weight Loss Improve Fertility?

Does weight loss before fertility treatment improve live birth? The best trial found no benefit. Here is what couples should know about diet, exercise, sperm, GLP-1s, and pregnancy.

calorie restrictionfertilityobesitymetabolic syndrome

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Mar 17, 2026Sleep

Mediterranean Lifestyle and Sleep Apnea: What Lasts Beyond Weight Loss

A Mediterranean lifestyle improved metabolic health after sleep apnea treatment. Here's what MIMOSA found, where weight loss fits, and what remains unknown.

sleep apneacpapmediterranean dietmetabolic syndrome

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Mar 15, 2026Nutrition

Mediterranean Diet for Metabolic Disease: What 69 Studies Show

A 69-study guideline review links Mediterranean diet adherence with lower mortality in metabolic disease. The HbA1c evidence is less certain.

mediterranean diettype 2 diabeteshba1cmetabolic syndrome

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Mar 15, 2026Nutrition

Anthocyanins and Heart Health: Lipid Gains, Glycemic Limits

Do anthocyanin-rich foods improve cholesterol or blood sugar? Review 47 RCTs, a T2DM bilberry trial, and gut-microbiome claims.

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