Apr 6, 2026Mental Health

Curcumin, Exercise, and Mood: The Synergy Claim Has a Gap

Aerobic exercise and bioavailable curcumin each have mood evidence, but no human trial has shown their combination beats exercise alone.

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Mar 29, 2026Mental Health

Purple Perilla for Memory: What the First RCT Shows

Can purple perilla extract improve memory? The first placebo-controlled trial found a positive signal, but missing effect sizes and zero replication limit it.

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Mar 25, 2026Physical Activity

Home Exercise in Huntington’s: Real Gains, Limited Proof

Home-based exercise improved motor function and quality of life in Huntington's disease trials. What that does and does not mean for brain health.

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Mar 24, 2026Mental Health

Mind-Body Practices Can Shift Stress Biomarkers—With Limits

An 89-RCT review links mindfulness, yoga, and related practices to lower cortisol and inflammation, but active controls complicate the story.

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Mar 19, 2026Nutrition

Intermittent Fasting, BDNF, and Depression: What Holds Up

Does intermittent fasting raise BDNF and ease depression? Human studies show fewer cravings for some people, but an uneven BDNF signal and no MDD trials.

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Mar 18, 2026Mental Health

Meditation, BDNF, and the Hippocampus: What One Trial Found

A nine-month meditation trial linked lower cortisol, higher serum BDNF, and dentate gyrus growth. The result is intriguing, but unreplicated.

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Mar 16, 2026Mental Health

CoQ10 for Depression: A Real Signal, Many Unknowns

A 2025 meta-analysis found lower depression scores with CoQ10, but small, mixed trials leave a key question: who is actually likely to benefit?

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Mar 8, 2026Physical Activity

Resistance Training May Raise BDNF More Than Cardio

A 39-trial network meta-analysis ranked resistance training above HIIT and aerobic exercise for serum BDNF. The catch: BDNF may not predict cognition.

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Mar 7, 2026Mental Health

Mind-Body Exercise, Inflammation, and Mental Health

Tai Chi, yoga, qigong, and MBSR may affect neuroinflammation in mental disorders, but the biomarker you measure can change the answer.

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