Jul 11, 2026Body Composition

Why Exercise Matters for Lean Mass During Weight Loss

Dieting can cost lean mass, especially without exercise. New research links baseline insulin sensitivity to risk and treats FGF19 as an early clue.

lean massweight lossresistance trainingaerobic exercise

Read article →

Jun 16, 2026Metabolic Aging

Does Sitting Less Improve Liver Insulin Sensitivity?

A six-month trial found that sitting less did not clearly improve liver insulin sensitivity or liver fat—while weight-loss studies reveal why.

insulin sensitivityliver fatmetabolic syndromesedentary behavior

Read article →

Jun 15, 2026Caloric Restriction

Severe Calorie Restriction Improved Prediabetes—Not Aging

An 8-week low-energy diet rapidly improved prediabetes markers, but its molecular-rejuvenation claim rests on surrogate proteins from only 44 high responders.

calorie restrictionprediabetesweight lossinsulin resistance

Read article →

Jun 15, 2026Caloric Restriction

Intermittent Fasting Works for Fat Loss, Not Proven Autophagy

Intermittent fasting can help reduce body fat, but human trials show no reliable calorie-independent edge—and claims of whole-body autophagy still outrun proof.

intermittent fastingtime-restricted eatingautophagycalorie restriction

Read article →

Jun 14, 2026Metabolic Therapeutics

Tirzepatide vs. Semaglutide: More Fat Loss, Not Proven Appetite Edge

A 28-week head-to-head trial found greater weight and fat loss with tirzepatide than semaglutide 1 mg—but appetite superiority remains unproven.

tirzepatidesemaglutideweight losstype 2 diabetes

Read article →

Apr 29, 2026Sleep

Can Better Sleep Help You Lose Weight? What Trials Show

Can better sleep support weight loss? A 2026 meta-analysis finds modest benefits for poor sleepers, but sleep is no standalone obesity treatment.

cbt-isleep hygieneweight lossbmi

Read article →

Mar 29, 2026Cardiometabolic Drugs

Tirzepatide Safety in Heart-Risk Diabetes: What We Know

Tirzepatide can improve weight and glucose control, but what do cardiovascular-risk trials show about nausea, serious harm, and mortality?

tirzepatideglp-1 agonisttype 2 diabetescardiovascular risk

Read article →

Mar 27, 2026Metabolic Health

Tirzepatide and MASH: Can Weight Loss Track Liver Healing?

Tirzepatide resolved MASH on biopsy in phase 2 data. Can 10% weight loss, triglycerides, and MRI markers help track liver response?

tirzepatidemashliver fibrosisweight loss

Read article →

Mar 27, 2026Cardiovascular Health

GLP-1 Drugs and Heart Failure: What an NNT of 80 Means

GLP-1 drugs reduce heart failure events modestly overall, with stronger signals in obesity. See what the NNTs, limits, and next-generation drugs mean.

glp-1 agonistssemaglutidetirzepatideheart failure

Read article →

Mar 27, 2026Nutrition

Oral Semaglutide and Fatty Liver: What a 28-Week Trial Shows

Can oral semaglutide help fatty liver disease? A 28-week obesity trial found weight loss and lower liver stiffness, but fibrosis evidence remains incomplete.

semaglutideglp-1liver fibrosisnafld

Read article →

Mar 26, 2026Nutrition

Fiber, Probiotics, Chromium: What This Weight-Loss RCT Shows

A lifestyle RCT produced about 5 kg of weight loss in four weeks, but bundled fiber, probiotics, chromium, diet counseling, and time-restricted eating.

weight losstime-restricted eatingprobioticslactobacillus

Read article →

Mar 26, 2026Nutrition

Psyllium for Weight Loss: Useful Fiber, Modest Evidence

Can psyllium husk support weight loss? Six small randomized trials suggest modest benefits, but the evidence does not establish glucose or LDL effects.

psyllium huskdietary fiberweight lossgut motility

Read article →

Page 1 of 3Next →