Apr 5, 2026NutritionCitrus Flavonoids With Metformin: One Small TrialCan citrus flavonoids improve prediabetes outcomes on metformin? One small trial found lower OGTT glucose, but replication and safety data are missing.metformincitrus flavonoidsprediabetesglucose controlRead article →
Mar 28, 2026Cardiovascular HealthHow SGLT2 Inhibitors Protect Failing Hearts Beyond Blood SugarSGLT2 inhibitors cut heart-failure risk beyond glucose control. What trials, remodeling data, mechanisms, safety limits, and cardio-oncology gaps show.sglt2 inhibitorsautophagyheart failureampkRead article →
Mar 27, 2026Physical ActivityExercise, FGF21, and SIRT3: A Diabetic Heart HypothesisExercise changes FGF21 in type 2 diabetes, while SIRT3 falls in cardiometabolic disease. Can this pathway repair diabetic-heart mitochondria?sirt3mitochondrial dysfunctionfgf21type 2 diabetesRead article →
Mar 17, 2026Physical ActivityPreventing Gestational Diabetes in High-Risk PregnancyExercise has the clearest RCT evidence for preventing gestational diabetes in high-risk pregnancy. Mediterranean eating may add benefit.gestational diabetesexerciseglucose disposalglut4Read article →
Mar 17, 2026NutritionIntermittent Hypoxia Training: Metabolic Promise, Missing ProofIntermittent hypoxia training plus fasting produced weight loss in obesity studies, but evidence for IHT alone remains thin and contradictory.intermittent fastingintermittent hypoxia traininginsulin sensitivityweight lossRead article →
Mar 16, 2026Physical ActivityConcurrent Training After 50: The Protein and Order EvidenceConcurrent training after 50 can build fitness and strength. What 49 trials say about protein, exercise order, and the real interference effect today.concurrent trainingresistance trainingcardiomuscle strengthRead article →