Mar 27, 2026NutritionNAD+ and Heart Failure: Why SIRT3 May Not Be the AnswerNR and NMN raise blood NAD+ in humans, but cardiac benefits remain unproven—and mouse data challenge the usual SIRT3 explanation.nad+nmnsirt3heart failureRead article →
Mar 27, 2026Physical ActivityExercise, FGF21, and SIRT3: A Diabetic Heart HypothesisExercise changes FGF21 in type 2 diabetes, while SIRT3 falls in cardiometabolic disease. Can this pathway repair diabetic-heart mitochondria?sirt3mitochondrial dysfunctionfgf21type 2 diabetesRead article →