Cardiorespiratory Fitness and Mortality: The Dose-Response
Cardiorespiratory fitness and VO2max predict mortality in large cohorts. Learn the per-MET gradient, who benefits most, and where the evidence has limits.
Mitochondrial Optimization Claims: What Three Studies Actually Show
Three papers on mitochondria are being cited to push supplements. We read them. Two use mouse gene knockouts. One covers sepsis. None tell you what to do.
20 Longevity Studies, Zero Human Data: What Science Really Says
NMN, senolytics, mTOR, and dietary restriction—20 studies, six mechanisms, eight species. One problem: none of it proves you'll live longer. We break it down.
Probiotic Hype vs. Reality: What Four New Studies Actually Prove
Four probiotic studies are being hyped as precision longevity medicine. The truth: monkeys, chickens, and zero human trials. Here's what the research really shows.
Senolytics and Rejuvenation: What the Research Actually Shows
Zombie cells, parabiosis, and a heart failure drug — senolytics are real science. The rejuvenation marketing layered on top isn't. We reviewed all three papers.
Dasatinib + Quercetin: Senolytics Hype vs. Human Evidence
Senolytics like dasatinib and quercetin dominate biohacking forums. The problem: every supporting study is in mice. Here's what the evidence actually shows.
Gut Microbiome and Longevity: What the Science Actually Proves
Three papers cite gut microbiome research to claim aging is fixable. We reviewed each one. Here's what the evidence actually supports — and what it doesn't.