Jun 15, 2026Caloric Restriction

Intermittent Fasting Works for Fat Loss, Not Proven Autophagy

Intermittent fasting can help reduce body fat, but human trials show no reliable calorie-independent edge—and claims of whole-body autophagy still outrun proof.

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Mar 25, 2026Neurodegeneration

Can GV-971 Really Rank With Donepezil for Alzheimer’s?

A critical look at Alzheimer's drug rankings: why GV-971's China-only evidence differs from ChEIs, memantine, and amyloid antibodies.

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Mar 22, 2026Nutrition

Which Probiotic Strain Is Best for IBS? The Evidence

Bacillus coagulans tops an IBS probiotic ranking, but strain trials, Rome IV data, dose differences, and follow-up reveal no simple winner.

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Mar 18, 2026Nutrition

Ketogenic Diet for Cancer: What Clinical Trials Actually Show

Can keto help treat cancer? Review the randomized trials, safety concerns, and why no MCT dose for therapeutic ketosis is proven in cancer patients.

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Mar 17, 2026Cancer Prevention

Breast Cancer Prevention Drugs: What an NMA Ranking Means

A 43-trial network meta-analysis ranked diabetes drugs above tamoxifen for breast cancer prevention. Sparse data make that result hard to trust.

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Mar 17, 2026Nutrition

Mediterranean Diet and Depression: What Trials Actually Show

Can a Mediterranean diet ease clinical depression? Randomized trials find symptom improvements, but low-certainty evidence keeps it adjunctive.

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Mar 17, 2026Mental Health

Probiotics for Childhood Depression: What the Null Result Means

A 2024 meta-analysis found no benefit from probiotics for pediatric depression—but none of its trials enrolled children diagnosed with depression.

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Mar 13, 2026Physical Activity

Wearable Trackers Don’t Sustain Activity on Their Own

Wearable activity trackers can measure movement, but two randomized trials found they did not sustain activity or cut sitting without stronger support.

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