Mar 23, 2026Gut Health

FMT for IBS: Quality-of-Life Signal, No Durable Proof

Does fecal microbiota transplantation help IBS? Meta-analyses find better quality of life, but durable symptom relief and guideline support remain uncertain.

fecal microbiota transplantibsgut microbiomedysbiosis

Read article →

Mar 22, 2026Gut Health

Ethosuximide Fell Behind Placebo in an IBS Pain Trial

An epilepsy drug targeting T-type calcium channels lagged placebo in an IBS pain trial. What the result says, and cannot say, about visceral pain.

ibsethosuximidecav3.2visceral pain

Read article →

Mar 22, 2026Biomarkers

AI for IBS Diagnosis: Why 99% Accuracy Is Not Enough

AI models report up to 99% accuracy for IBS diagnosis, but six small case-control studies and zero external validations leave major gaps.

gut microbiomeibsai diagnosticsmicrobiome biomarker

Read article →

Mar 22, 2026Gut Brain Axis

IBS Is a Gut-Brain Disorder. Which Therapy Ranks First?

IBS is now classified as a disorder of gut-brain interaction. A Lancet analysis ranks behavioral therapies—but the top score is far from final.

ibsgut-brain axisbehavioral therapygut microbiome

Read article →

Mar 22, 2026Mental Health

Can BL NCC3001 Explain the IBS Gut-Brain Link?

BL NCC3001 changed metabolites linked with mood in a small IBS trial. The gut-brain mechanism is intriguing, but far from proven.

probioticsgut microbiomepsychobioticsdepression

Read article →

Mar 22, 2026Nutrition

Which Probiotic Strain Is Best for IBS? The Evidence

Bacillus coagulans tops an IBS probiotic ranking, but strain trials, Rome IV data, dose differences, and follow-up reveal no simple winner.

probioticsibsbacillus coagulansgut microbiome

Read article →

Mar 22, 2026Nutrition

Which Probiotics Help IBS? The Strain-by-Strain Evidence

A 2024 meta-analysis of 82 IBS trials identifies Escherichia strains as the best-supported probiotic option—and shows why most products remain uncertain.

probioticsibsgut microbiomeescherichia

Read article →