Apr 6, 2026

Blue-Light Glasses for Mania: The Best Trial Found No Benefit

Can amber glasses stabilize bipolar mood? A blinded inpatient trial found no benefit for acute mania, despite a plausible circadian mechanism.

bipolar disorderblue lightamber glasses

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Apr 6, 2026

Blue Light at Work: Why Color Temperature Misleads

Blue-enriched office light can improve alertness, but color temperature misleads. What mel-EDI research says about focus, sleep, and timing.

blue lightmelanopsincircadian rhythm

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Apr 6, 2026

Curcumin, Exercise, and Mood: The Synergy Claim Has a Gap

Aerobic exercise and bioavailable curcumin each have mood evidence, but no human trial has shown their combination beats exercise alone.

bdnfcurcuminaerobic exercise

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Apr 1, 2026

Can Probiotics or Guided Imagery Change Cortisol?

Two randomized trials tested a kefir probiotic strain and guided imagery for cortisol. The signals were small, mixed, and far from practical proof.

hpa axiscortisolstress response

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Mar 30, 2026

Meditation, HRV, and Two Different Routes to Regulation

MBSR may improve how people use cardiac signals during emotion regulation, while slow breathing raises HRV during practice. What the evidence supports.

mbsrhrvmeditation

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Mar 30, 2026

Can Positive Affect Raise HRV? What 36 Studies Really Show

A 2025 review links calm positive affect with higher resting HRV, but excitement can lower it—and causation remains unproven.

hrvvagal tonepositive affect

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Mar 29, 2026

tDCS for Alzheimer’s: Does a Lower Dose Work Better?

A 2025 meta-analysis links lower tDCS current density with cognitive gains in Alzheimer's and MCI—but healthy-brain enhancement remains unproven.

tdcscognitive declinealzheimer's disease

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Mar 29, 2026

Purple Perilla for Memory: What the First RCT Shows

Can purple perilla extract improve memory? The first placebo-controlled trial found a positive signal, but missing effect sizes and zero replication limit it.

purple perillacognitive impairmentneuroprotection

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Mar 27, 2026

Desk Sitting and Mental Health: What the Evidence Actually Shows

Does desk sitting harm mental health? Evidence links self-reported work sitting to risk, but device data and long-term activity studies complicate the story.

occupational sittingburnoutpsychological distress

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Mar 27, 2026

Sit Smarter, Eat Mediterranean: What Brain Aging Studies Show

Reading and complex work while seated may track with lower dementia risk. Mediterranean eating also supports cognitive aging—but neither is proven causal.

dementiacognitive activitysedentary behavior

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Mar 25, 2026

PMSB-E Trial: Exercise Improved Function, Not Mood

A 427-person trial found lasting physical-function gains but no depression or anxiety benefit. What PMSB-E can and cannot tell older adults.

depressionolder adultsexercise

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Mar 25, 2026

Digital Behavioral Activation Apps: Short-Term Help, Unclear Staying Power

Digital behavioral activation apps can ease depression symptoms short term, but evidence on six-month benefits and the value of human guidance remains incomplete.

behavioral activationdepression treatmentdigital therapeutics

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