Jul 11, 2026Aging Clocks

Can Calorie Restriction Move Biological Aging Metrics?

A two-year randomized calorie-restriction trial moved some aging biomarkers, but mixed clock results show why no test can yet certify slower aging.

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Jul 8, 2026Cellular Senescence

Can Senescent Cells Be Rejuvenated Instead of Removed?

Can nutrition or stress reduction rejuvenate senescent cells? Human studies show shifts in SASP biomarkers, but durable cell reversal remains unproven.

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Mar 20, 2026Nutrition

What a 10-Day Modified Fast Actually Does to Muscle

Does extended fasting burn muscle? A 10-day trial suggests much early lean-mass loss is water and glycogen, but the evidence has major limits.

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Mar 19, 2026Nutrition

Keto for Fatty Liver: Why Your PNPLA3 Gene May Matter

Can keto reduce fatty liver? Evidence points to weight loss and Mediterranean diets, while PNPLA3 genetics raise unanswered questions about ketogenic diets.

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Mar 14, 2026Nutrition

Fasting, Calorie Cuts, or Keto: What Lowers Inflammation?

Intermittent fasting, calorie restriction, and keto can lower inflammatory biomarkers—but matched-weight studies question whether diet format matters.

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Mar 9, 2026Physical Activity

How to Protect Muscle While Losing Fat: What the Trials Show

Resistance training protects lean mass during weight loss. Here's what trials say about protein, whey, BCAAs, fasting, and medical diets.

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Mar 8, 2026Muscle Preservation

Knee OA Weight Loss: Exercise and Protein to Preserve Muscle

Can you lose weight with knee osteoarthritis without sacrificing muscle? Network meta-analyses favor resistance-led exercise plus nutrition, with caveats.

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Mar 6, 2026Nutrition

Diet or HIIT Twice a Week for Blood Sugar? What RCTs Show

Two randomized trials tested a simple question: if you only commit two hard days a week, should you cut calories or do HIIT for blood sugar?

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