Mar 28, 2026Physical Activity

Muscle Memory After a Break: What Human Studies Show

Muscle memory survives short training breaks, but human myonuclei can decline with long inactivity. What HIIT epigenetics and aging research show.

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Mar 28, 2026Physical Activity

Exercise May Methylate Inflammatory Genes in Immune Cells

Exercise changed immune-cell DNA methylation in older women and women with PCOS, but the evidence does not yet prove targeted gene silencing.

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Mar 28, 2026Physical Activity

Diet, Exercise, and DNA Methylation After Major Weight Loss

Can diet and exercise alter DNA methylation? One 12-month study in severely obese hypogonadal men found leukocyte shifts, but not proof of fat-cell change.

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Mar 12, 2026Aging Biomarkers

Histone Clocks Could Track Age Across Species—But It’s Early

Histone modification clocks may estimate age even in species without DNA methylation. Here's what a 2026 study found—and why validation comes first.

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Feb 24, 2026Mental Health

Five Brain Studies, Zero Coherence: The Neuroinflammation Myth

Five studies bundled as 'neuroinflammation research' — one failed replication, one was a mouse stroke model. Here's why none of it is actionable for you.

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