Jul 13, 2026Aging Biomarkers

Brain Age Gaps Map Aging Biology, Not Anti-Aging Cures

Brain age gaps link MRI, genetics, metabolism, and dementia risk—but they remain research biomarkers, not proof that a treatment slows aging.

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Jul 10, 2026Microbiome & Aging

Gut Microbiome and Longevity: What Causal Studies Show

Can gut microbes influence exceptional longevity? Family cohorts and Mendelian randomization find recurring signals, but no proven lifespan treatment yet.

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Mar 27, 2026Hormones

PCOS Causes: What Mendelian Randomization Can—and Can’t—Show

A 2024 Mendelian randomization screen links insulin resistance, inflammation, gut microbes, and iron biology to PCOS risk—with major caveats.

pcosinsulin resistanceadipositygut microbiome

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Mar 27, 2026Nutrition

Omega-6 and Myocarditis: A Genetic Signal, Not a Diet Rule

A Mendelian randomization study links genetically higher omega-6 levels to myocarditis risk, but missing effect sizes and pleiotropy limit action.

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Mar 27, 2026Nutrition

Diet and Hair Loss: What a Large Genetic Study Really Found

A 2025 genetic study linked food preferences to androgenetic alopecia and alopecia areata. Why alcohol merits attention—and melon does not.

hair lossmendelian randomizationandrogenetic alopeciadietary patterns

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Mar 27, 2026Biomarkers

Why BMI May Not Be an Independent Multimorbidity Driver

A Mendelian randomization study reshuffles cardiometabolic priorities: BMI and screen time may act through blood pressure and glucose.

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Mar 27, 2026Nutrition

DASH Diet and Sarcopenia: Association, Not Proof

A new DASH diet study links higher adherence with less sarcopenia. Its genetic analysis adds clues, but it does not prove DASH preserves muscle.

dash dietsarcopeniamendelian randomizationmuscle preservation

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Mar 22, 2026Nutrition

Does Genetic Evidence End the Case for “Healthy” Alcohol?

A 337,463-person Mendelian-randomization study links alcohol to 22 diseases and finds no protective low-dose curve. What the evidence can and cannot prove.

alcoholj-curve hypothesismendelian randomizationconfounding bias

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