Mar 28, 2026Physical Activity

Exercise Is Linked to a Younger Muscle Epigenome

Exercise and VO2max are linked to younger skeletal-muscle methylation and gene-expression profiles. The Yamanaka-factor connection remains unproven.

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Mar 27, 2026Nutrition

Why NAD+ Supplements May Miss the Problem in Diabetic Hearts

New diabetic-heart research links ACMSD to impaired NAD+ synthesis, while the only heart-failure NAD+ trial leaves HFpEF treatment unanswered in humans.

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Mar 24, 2026Physical Activity

HFpEF Exercise: Why HIIT Did Not Beat Moderate Training

In HFpEF, HIIT and moderate exercise both improved peak VO2 versus advice alone. The largest trial explains why harder intervals did not win.

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Mar 21, 2026Metabolic Aging

Older Adults With Type 2 Diabetes Need More Than HbA1c

For older adults with type 2 diabetes, long-term diet plus multicomponent exercise improved HbA1c, fitness, and function in one RCT.

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