Jul 2, 2026Hormonal Aging

Early Menopause Hormone Therapy: Timing, Risks, and Reality

Does starting menopause hormone therapy before 60 protect the heart or brain? Randomized evidence finds timing signals, but no proven longevity benefit.

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Mar 29, 2026Longevity Research

Do Sex Hormones Slow Epigenetic Aging? The Best Test Says No

A 1,404-person study tested estradiol, DHEAS, and testosterone-related measures against six epigenetic clocks. The results were inconsistent.

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Mar 26, 2026Fertility

IVF E2/P Ratio Before Progesterone: Signal, Not a Target

An IVF study of 25,000 HRT-FET cycles links the estradiol-to-progesterone ratio before progesterone to live birth, but weak accuracy limits clinical use.

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Mar 18, 2026Mental Health

How Hormones May Shape Fear Learning—and What the Pill Changes

Estradiol, progesterone, and oral contraceptives may shape fear learning. What human studies say about PTSD risk, safety memory, and uncertainty.

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