Mar 28, 2026Physical Activity

Diet, Exercise, and DNA Methylation After Major Weight Loss

Can diet and exercise alter DNA methylation? One 12-month study in severely obese hypogonadal men found leukocyte shifts, but not proof of fat-cell change.

dna methylationdnmtexerciseobesity

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Mar 28, 2026Physical Activity

Exercise Is Linked to a Younger Muscle Epigenome

Exercise and VO2max are linked to younger skeletal-muscle methylation and gene-expression profiles. The Yamanaka-factor connection remains unproven.

vo2 maxepigenetic agedna methylationexercise training

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Mar 12, 2026Epigenetics

Volunteering and Epigenetic Aging: A Promising Link

Does volunteering slow biological aging? Older-adult studies link social purpose to favorable epigenetic clocks, but causation remains unproven so far.

epigenetic clocksdna methylationbiological agingphenoage

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Mar 12, 2026Aging Biomarkers

Histone Clocks Could Track Age Across Species—But It’s Early

Histone modification clocks may estimate age even in species without DNA methylation. Here's what a 2026 study found—and why validation comes first.

dna methylationhistone modificationsbiological agingepigenetics

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