Jul 2, 2026Hormonal Aging

Early Menopause Hormone Therapy: Timing, Risks, and Reality

Does starting menopause hormone therapy before 60 protect the heart or brain? Randomized evidence finds timing signals, but no proven longevity benefit.

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Jun 25, 2026Frailty

Frailty May Predict Lost Healthy Years Before Disease

Frailty may flag fewer disease-free years and higher cardiovascular risk before diagnosis. Here's what prospective studies show—and what they cannot prove.

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Mar 23, 2026Physical Activity

CBT or Mindfulness Plus Fitbit: The 3-Step Problem

A trial in depressed cardiovascular patients found self-guided CBT or mindfulness plus Fitbit added about 3 daily steps—and the effect vanished after eight weeks.

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Mar 16, 2026Physical Activity

Lifestyle Lowers Heart Risk Across Genetic Profiles, With Limits

Studies across European, Korean, Norwegian, and U.S. cohorts link fitness, diet, and no smoking to lower cardiovascular risk at every genetic tier.

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Mar 16, 2026Nutrition

What Lifestyle RCTs Actually Prove for Heart Disease

Mediterranean diet trials support fewer cardiovascular events, but the popular 66% lifestyle risk-reduction claim comes largely from observational evidence.

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Mar 16, 2026Genetic Predisposition

TV Time, Diabetes Genes, and Heart Risk: What We Know

UK Biobank studies link TV viewing and diabetes genetic risk to heart disease. Here's what the data show, where they conflict, and what to do.

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Mar 16, 2026Physical Activity

Wearables Reprice Exercise: Vigorous, Moderate, and Light

Wearable studies suggest vigorous exercise delivers more mortality benefit per minute than guidelines assume, while light activity helps but cannot replace it.

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Mar 14, 2026Nutrition

GLP-1 Heart Benefits Are Real. The RAS Mechanism Isn’t.

GLP-1 drugs reduce cardiovascular events in high-risk diabetes, but the proposed renin-angiotensin mechanism remains unproven.

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Mar 14, 2026Nutrition

Mediterranean Diet: Heart Benefits Before and After CVD

Mediterranean diet adherence is linked to 12% lower stroke risk before CVD and lower all-cause mortality after diagnosis. The limits matter.

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Mar 13, 2026Nutrition

AHEI and DASH Lead Diet-Score Evidence—But Labels Matter Less

An umbrella review ranks AHEI and DASH highest for mortality, heart disease, and diabetes evidence. The bigger finding: their shared food pattern wins.

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Mar 11, 2026Cardiovascular Health

Sauna and Heat Therapy Lower Blood Pressure—Modestly

Two RCT meta-analyses find regular sauna and passive heat therapy lower blood pressure by about 4 mmHg, but broader benefits remain unproven.

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Feb 28, 2026Metabolic Health

Semaglutide Protects Kidneys and Reverses Prediabetes in SELECT Trial

SELECT secondary analyses: semaglutide cut kidney risk 22%, diabetes progression 78% in non-diabetic obese adults. Real signal, real caveats — full breakdown.

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