Mar 28, 2026Physical ActivityExercise Is Linked to a Younger Muscle EpigenomeExercise and VO2max are linked to younger skeletal-muscle methylation and gene-expression profiles. The Yamanaka-factor connection remains unproven.vo2 maxepigenetic agedna methylationexercise trainingRead article →
Mar 28, 2026Aging BiomarkersCould High Glucose Drain Muscle NAD+? The EvidenceA new mouse study links high glucose to muscle NAD+ loss. Here is what exercise, NMN, coffee, and human evidence actually show.nad+glucose sensingsarcopeniaparp1Read article →
Mar 25, 2026NutritionNAD+ Precursors for Aging Muscle: Beyond NMNA coffee-derived NAD+ precursor tracks with sarcopenia, but human trials still leave NMN, NR, trigonelline, and muscle aging unresolved.trigonellinenad+sarcopeniamuscle agingRead article →
Mar 15, 2026Physical ActivityExercise Rebuilds Muscle Capillaries—but Not Yet Stem CellsResistance training can increase muscle capillaries with age, but human trials have not shown that this restores muscle stem cells or differs by sex.resistance trainingcapillary densitysarcopeniamuscle agingRead article →
Mar 8, 2026NutritionNMN and NR for Aging Muscle: What RCTs Actually ShowDo NMN and NR improve muscle, strength, or walking speed with age? The first pooled RCT evidence finds no proven sarcopenia benefit yet.nmnnrnad+sarcopeniaRead article →