Mar 22, 2026Nutrition

Tetradesmus obliquus Extract: A First Human Trial, Not Proof

A first pilot RCT of Tetradesmus obliquus found lower GI symptom scores, but microbiome results and butyrate data leave major questions.

gut microbiomemicroalgae extractbutyrateshort-chain fatty acids

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Mar 22, 2026Nutrition

Crohn's Diet Paradox: Opposite Plans Can Induce Remission

Crohn's diets can eliminate fiber or emphasize whole foods, yet both may induce remission. What trials reveal about EEN, CDED, symptoms, and limits today.

crohn's diseaseexclusive enteral nutritionwhole food dietgut microbiome

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Mar 22, 2026Biomarkers

AI for IBS Diagnosis: Why 99% Accuracy Is Not Enough

AI models report up to 99% accuracy for IBS diagnosis, but six small case-control studies and zero external validations leave major gaps.

gut microbiomeibsai diagnosticsmicrobiome biomarker

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Mar 22, 2026Gut Microbiome

Ulcerative Colitis: Where FMT Fits Against Modern Drugs

A 2021 analysis ranked FMT with infliximab and vedolizumab for UC induction. Newer evidence puts that result in sharper context.

fmtulcerative colitisgut microbiomebiologics

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Mar 22, 2026Gut Brain Axis

IBS Is a Gut-Brain Disorder. Which Therapy Ranks First?

IBS is now classified as a disorder of gut-brain interaction. A Lancet analysis ranks behavioral therapies—but the top score is far from final.

ibsgut-brain axisbehavioral therapygut microbiome

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Mar 22, 2026Gut Microbiome

Probiotics for Autism GI Symptoms: What the Evidence Shows

A 2025 meta-analysis found gut interventions eased GI symptoms in autistic children, but evidence does not show they improve core autism traits.

bifidobacteriumautism spectrum disordergut microbiomeprobiotics

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Mar 22, 2026Gut Health

Probiotics for Elderly Constipation: What the Trials Show

Do probiotics help elderly constipation? Review B. lactis trials, FMT rankings, PEG evidence, doses, safety gaps, and practical limits.

fmtprobioticsconstipationgut microbiome

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Mar 22, 2026Nutrition

Can LP299V Make Ferrous Sulfate Easier to Tolerate?

One trial found LP299V cut reported GI side effects from oral iron. See what the probiotic evidence supports, and where the study falls short.

iron deficiency anemiairon supplementationprobioticslactiplantibacillus plantarum

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Mar 22, 2026Mental Health

Can BL NCC3001 Explain the IBS Gut-Brain Link?

BL NCC3001 changed metabolites linked with mood in a small IBS trial. The gut-brain mechanism is intriguing, but far from proven.

probioticsgut microbiomepsychobioticsdepression

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Mar 22, 2026Nutrition

Which Probiotic Strain Is Best for IBS? The Evidence

Bacillus coagulans tops an IBS probiotic ranking, but strain trials, Rome IV data, dose differences, and follow-up reveal no simple winner.

probioticsibsbacillus coagulansgut microbiome

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Mar 22, 2026Nutrition

Which Probiotics Help IBS? The Strain-by-Strain Evidence

A 2024 meta-analysis of 82 IBS trials identifies Escherichia strains as the best-supported probiotic option—and shows why most products remain uncertain.

probioticsibsgut microbiomeescherichia

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Mar 22, 2026Nutrition

Mediterranean Diet, Gut Microbes, and Endocannabinoids

An isocaloric trial found Mediterranean eating shifted endocannabinoid-related blood ratios, with Akkermansia correlations—but causality remains unproven.

endocannabinoid systemmediterranean dietanandamidegut microbiome

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