Semaglutide Helps a Specific Kind of HFpEF—Not All
Semaglutide improved symptoms and walking capacity in obesity-related HFpEF, but the evidence does not support cardiac use for every patient—or biohacker.
GLP-1 Drugs in Heart Failure: Real Promise, Tight Limits
Meta-analyses suggest GLP-1 drugs help obese patients with HFpEF feel and function better, but no trial has shown longer survival or clear benefit in HFrEF.